2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Angiotensin-converting Enzyme (ACE)
  5. Angiotensin-converting Enzyme (ACE) Modulator

Angiotensin-converting Enzyme (ACE) Modulator

Angiotensin-converting Enzyme (ACE) Modulator (1):

Cat. No. Product Name Effect Purity
  • HY-N0217
    Benzoylaconine
    		Modulator 99.92%
    Benzoylaconine (Benzoylaconitine) is an orally active monoester alkaloid found in the traditional Chinese medicine Aconitum carmichaelii. Benzoylaconine is an ACE2 agonist (EC50: 1.5 μM) with antihypertensive and anti-heart failure effects. Benzoylaconine inhibits TLR-induced MAPK and NF-κB pathways to exert anti-inflammatory effects. Benzoylaconine upregulates the protein levels of P-gp, MRP2, and has anti-tumor effects.